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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EPHA3
All Species:
22.42
Human Site:
Y123
Identified Species:
54.81
UniProt:
P29320
Number Species:
9
Phosphosite Substitution
Charge Score:
0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P29320
NP_005224.2
983
110131
Y123
C
K
E
T
F
N
L
Y
Y
M
E
S
D
D
D
Chimpanzee
Pan troglodytes
P0C0K6
1020
110674
Y131
C
R
E
T
F
T
L
Y
Y
R
Q
A
E
E
P
Rhesus Macaque
Macaca mulatta
XP_001083136
984
110275
Y123
C
K
E
T
F
N
L
Y
Y
M
E
S
D
D
D
Dog
Lupus familis
XP_545052
972
108820
E125
D
H
G
V
K
F
R
E
H
Q
F
T
K
I
D
Cat
Felis silvestris
Mouse
Mus musculus
P29319
983
109937
Y123
C
K
E
T
F
N
L
Y
Y
M
E
S
D
D
H
Rat
Rattus norvegicus
O08680
984
110209
Y123
C
K
E
T
F
N
L
Y
Y
M
E
S
D
D
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515041
956
107153
A120
T
K
I
D
T
I
A
A
D
E
S
F
T
Q
M
Chicken
Gallus gallus
P29318
983
109892
Y123
K
E
T
F
N
L
Y
Y
M
E
S
D
D
D
H
Frog
Xenopus laevis
Q91694
985
109711
Y125
C
K
E
T
F
N
L
Y
Y
Y
E
S
N
N
D
Zebra Danio
Brachydanio rerio
O13146
981
109636
E126
T
F
N
V
Y
Y
H
E
S
N
N
A
V
A
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
40.8
98.7
94.6
N.A.
95.6
95.6
N.A.
90.4
91.4
62.6
58.4
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
60.4
99
96.2
N.A.
97.6
97.4
N.A.
93.4
94.5
77.8
75.2
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
46.6
100
6.6
N.A.
93.3
100
N.A.
6.6
20
80
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
80
100
20
N.A.
93.3
100
N.A.
6.6
26.6
93.3
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
10
10
0
0
0
20
0
10
10
% A
% Cys:
60
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
0
10
0
0
0
0
10
0
0
10
50
50
50
% D
% Glu:
0
10
60
0
0
0
0
20
0
20
50
0
10
10
0
% E
% Phe:
0
10
0
10
60
10
0
0
0
0
10
10
0
0
0
% F
% Gly:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
10
0
0
0
0
10
0
10
0
0
0
0
0
20
% H
% Ile:
0
0
10
0
0
10
0
0
0
0
0
0
0
10
0
% I
% Lys:
10
60
0
0
10
0
0
0
0
0
0
0
10
0
0
% K
% Leu:
0
0
0
0
0
10
60
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
10
40
0
0
0
0
10
% M
% Asn:
0
0
10
0
10
50
0
0
0
10
10
0
10
10
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% P
% Gln:
0
0
0
0
0
0
0
0
0
10
10
0
0
10
0
% Q
% Arg:
0
10
0
0
0
0
10
0
0
10
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
10
0
20
50
0
0
0
% S
% Thr:
20
0
10
60
10
10
0
0
0
0
0
10
10
0
0
% T
% Val:
0
0
0
20
0
0
0
0
0
0
0
0
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
10
10
10
70
60
10
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _